Baby Safety / Compounds / Triphenyltin (TPT)

Is Triphenyltin (TPT) safe for babies and kids?

Very high risk for kids

Infants are more vulnerable to Triphenyltin (TPT) than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

What is triphenyltin (tpt)?

CAS number
668-34-8
Molecular formula
C18H16Sn
Molecular weight
351.03 g/mol
SMILES
C1=CC=C(C=C1)[Sn](C2=CC=CC=C2)C3=CC=CC=C3
PubChem CID
11476

Risk for babies

Very high risk

Infants are more vulnerable to Triphenyltin (TPT) than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

Neonates and infants up to 12 months have incomplete blood-brain barrier development, immature Phase I/II metabolic enzymes (particularly CYP3A4, UGT1A1), and higher gastrointestinal permeability. Equivalent doses produce higher internal concentrations and longer residence times.

What to do: Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

Risk for pregnant and nursing people

High risk

Aromatase inhibition — reduced estrogen critical for pregnancy maintenance.

Regulatory consensus

2 regulatory and scientific bodies have classified Triphenyltin (TPT). The classifications differ — that's the data.

AgencyYearClassificationNotes
EU2002Banned — not approved as pesticide; REACH restricted
EPA2002All food uses cancelled

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter triphenyltin (tpt)

  • Pesticide
  • Industrial Chemical

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Triphenyltin (TPT):

  • Mancozeb (dithiocarbamate)
    Trade-offs: Alternative approach; specific tradeoffs depend on application context, scale, and regulatory requirements. Full hazard assessment of alternative recommended before adoption to avoid regrettable substitution.
    Relative cost: 1.2-2×
  • Copper fungicides
    Trade-offs: Alternative approach; specific tradeoffs depend on application context, scale, and regulatory requirements. Full hazard assessment of alternative recommended before adoption to avoid regrettable substitution.
    Relative cost: 1.2-2×

Frequently asked questions

Is triphenyltin (tpt) safe for kids?

Infants are more vulnerable to Triphenyltin (TPT) than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

What should I do if my child is exposed to triphenyltin (tpt)?

Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

See Triphenyltin (TPT) in the baby app

Look up products containing triphenyltin (tpt), compare to alternatives, and explore the full data record.

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Sources (1)
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Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →