Baby Safety / Compounds / Triflumizole

Is Triflumizole safe for babies and kids?

High risk for kids

Infants are susceptible to Triflumizole through dietary residues on produce. Developing endocrine and hepatic systems increase vulnerability to antifungal compounds.

What is triflumizole?

Also known as: Trifloxystrobin, Trifloxystrobine, CGA 279202, trifloxy-strobin.

CAS number
141517-21-7
Molecular formula
C20H19F3N2O4
Molecular weight
408.4 g/mol
SMILES
CC(=NOCC1=CC=CC=C1C(=NOC)C(=O)OC)C2=CC(=CC=C2)C(F)(F)F
PubChem CID
11664966

Risk for babies

High risk

Infants are susceptible to Triflumizole through dietary residues on produce. Developing endocrine and hepatic systems increase vulnerability to antifungal compounds.

Neonates and infants up to 12 months have incomplete blood-brain barrier development, immature Phase I/II metabolic enzymes (particularly CYP3A4, UGT1A1), and higher gastrointestinal permeability. Equivalent doses produce higher internal concentrations and longer residence times.

What to do: Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

Risk for pregnant and nursing people

High risk

Prenatal exposure to Triflumizole may affect fetal development through endocrine disruption pathways. Several fungicide classes (azoles, dicarboximides) interfere with steroid biosynthesis.

Known reproductive toxicant (GHS H360) or confirmed endocrine disruptor. Placental transfer is presumed. Fetal exposure during critical developmental windows may cause structural malformations, growth restriction, or functional deficits.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Regulatory consensus

1 regulatory bodyhas classified Triflumizole.

AgencyYearClassificationNotes
EDC Assessment—Suspected endocrine disruptor

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter triflumizole

  • Agricultural Products — crop treatment, soil application
  • Food Chain — residue on produce, water contamination

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Triflumizole:

  • Integrated Pest Management (IPM); Biopesticides; Biological control
    Trade-offs: Combines biological, cultural, and targeted chemical controls; reduces overall chemical use 30-70%; requires trained practitioners and monitoring infrastructure; higher management complexity; proven effective at scale in many crop systems.
    Relative cost: 1.2-2×

Frequently asked questions

Is triflumizole safe for kids?

Infants are susceptible to Triflumizole through dietary residues on produce. Developing endocrine and hepatic systems increase vulnerability to antifungal compounds.

What products contain triflumizole?

Triflumizole appears in: crop treatment (Agricultural products); soil application (Agricultural products); residue on produce (Food chain); water contamination (Food chain).

What should I do if my child is exposed to triflumizole?

Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

See Triflumizole in the baby app

Look up products containing triflumizole, compare to alternatives, and explore the full data record.

Open in baby View raw API data

Sources (1)
  1. PubChem (2026) — database

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →