Baby Safety / Compounds / Saflufenacil

Is Saflufenacil safe for babies and kids?

Elevated risk for kids

Not medical or professional safety advice, and not a substitute for a qualified clinician — consult one. Full disclaimer →

(Babies-specific data is limited; this page draws from human pregnant context.) Prenatal exposure to Saflufenacil is a concern due to potential endocrine disruption and developmental toxicity. Agricultural communities show higher gestational exposure through drinking water.

What is saflufenacil?

The IUPAC name is 2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl]-N-[methyl(propan-2-yl)sulfamoyl]benzamide.

Also known as: Sharpen, Kixor, BAS 800 H, N'-[2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-(trifluoromethyl)-3,6-dihydro-1(2H)-pyrimidinyl)benzoyl]-N-isopropyl-N-methylsulfamide.

IUPAC name
2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl]-N-[methyl(propan-2-yl)sulfamoyl]benzamide
CAS number
372137-35-4
Molecular formula
C17H17ClF4N4O5S
Molecular weight
500.85 g/mol
SMILES
CC(C)N(C)S(=O)(=O)NC(=O)C1=CC(=C(C=C1Cl)F)N2C(=O)C=C(N(C2=O)C)C(F)(F)F
PubChem CID
11571392

Risk for babies

Elevated risk

Prenatal exposure to Saflufenacil is a concern due to potential endocrine disruption and developmental toxicity. Agricultural communities show higher gestational exposure through drinking water.

Suspected reproductive toxicant (GHS H361) or suspected endocrine disruptor. Precautionary approach warranted. Animal studies or limited human data suggest developmental toxicity potential.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Risk for pregnant and nursing people

Elevated risk

Prenatal exposure to Saflufenacil is a concern due to potential endocrine disruption and developmental toxicity. Agricultural communities show higher gestational exposure through drinking water.

Suspected reproductive toxicant (GHS H361) or suspected endocrine disruptor. Precautionary approach warranted. Animal studies or limited human data suggest developmental toxicity potential.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Regulatory consensus

2 regulatory and scientific bodies have classified Saflufenacil. The classifications differ — that's the data.

AgencyYearClassificationNotes
EPA2009Reduced-risk pesticide registration
EU2009Approved under Regulation (EC) 1107/2009

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter saflufenacil

  • Agriculture

Frequently asked questions

No FAQ entries generated.

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Sources (1)
  1. EPA Registration — Saflufenacil (Reduced Risk) — epa

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for medical, pediatric, legal, or regulatory advice. Why we built ALETHEIA →