Baby Safety / Compounds / Phantolide

Is Phantolide safe for babies and kids?

Context-dependent for kids

Infants are more vulnerable to Phantolide than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

What is phantolide?

Also known as: Acetyl hexamethyl indan, Ethanone, 1-(2,3-dihydro-1,1,2,3,3,6-hexamethyl-1H-inden-5-yl)-, 6-Acetyl-1,1,2,3,3,5-hexamethylindan, MUSK PHANTOLID.

CAS number
15323-35-0
Molecular formula
C17H24O
Molecular weight
244.37 g/mol
SMILES
CC1C(C2=C(C1(C)C)C=C(C(=C2)C)C(=O)C)(C)C
PubChem CID
47167

Risk for babies

Context-dependent

Infants are more vulnerable to Phantolide than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

Neonates and infants up to 12 months have incomplete blood-brain barrier development, immature Phase I/II metabolic enzymes (particularly CYP3A4, UGT1A1), and higher gastrointestinal permeability. Equivalent doses produce higher internal concentrations and longer residence times.

What to do: Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

Risk for pregnant and nursing people

Context-dependent

Regulatory consensus

1 regulatory bodyhas classified Phantolide.

AgencyYearClassificationNotes
EDC Assessment—Suspected endocrine disruptor

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter phantolide

  • Personal Care — perfume, soap, cosmetics
  • Consumer Products — cleaning products, candles

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Phantolide:

  • Lower-sensitization structural analog; Unscented formulation
    Trade-offs: Eliminates allergen risk entirely; consumer acceptance varies (some associate scent with cleanliness/efficacy); growing market segment; regulatory advantage in EU (no IFRA compliance needed).
    Relative cost: 1.2-2×

Frequently asked questions

Is phantolide safe for kids?

Infants are more vulnerable to Phantolide than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

What products contain phantolide?

Phantolide appears in: perfume (Personal care); soap (Personal care); cleaning products (Consumer products); candles (Consumer products).

What should I do if my child is exposed to phantolide?

Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

See Phantolide in the baby app

Look up products containing phantolide, compare to alternatives, and explore the full data record.

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Sources (1)
  1. PubChem (2026) — database

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →