Baby Safety / Compounds / OPP-Na

Is OPP-Na safe for babies and kids?

Context-dependent for kids

Infants are more vulnerable to OPP-Na than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

What is opp-na?

Also known as: Sodium 2-biphenylate, Sodium o-phenylphenate, Sodium ortho-phenylphenate, Natriphene.

CAS number
132-27-4
Molecular formula
C12H9NaO
Molecular weight
192.19 g/mol
SMILES
C1=CC=C(C=C1)C2=CC=CC=C2[O-].[Na+]
PubChem CID
23675735

Risk for babies

Context-dependent

Infants are more vulnerable to OPP-Na than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

Neonates and infants up to 12 months have incomplete blood-brain barrier development, immature Phase I/II metabolic enzymes (particularly CYP3A4, UGT1A1), and higher gastrointestinal permeability. Equivalent doses produce higher internal concentrations and longer residence times.

What to do: Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

Risk for pregnant and nursing people

Context-dependent

Regulatory consensus

1 regulatory bodyhas classified OPP-Na.

AgencyYearClassificationNotes
EDC Assessment—Suspected endocrine disruptor

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter opp-na

  • Consumer Products — various

Safer alternatives

Lower-risk approaches that achieve a similar outcome to OPP-Na:

  • H2O2; UV
    Trade-offs: Alternative approach; specific tradeoffs depend on application context, scale, and regulatory requirements. Full hazard assessment of alternative recommended before adoption to avoid regrettable substitution.
    Relative cost: 1.2-2×

Frequently asked questions

Is opp-na safe for kids?

Infants are more vulnerable to OPP-Na than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

What products contain opp-na?

OPP-Na appears in: various (Consumer products).

What should I do if my child is exposed to opp-na?

Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

See OPP-Na in the baby app

Look up products containing opp-na, compare to alternatives, and explore the full data record.

Open in baby View raw API data

Sources (1)
  1. PubChem (2026) — database

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →