Is Naled safe for babies and kids?
High risk for kidsInfants are acutely vulnerable to Naled due to immature acetylcholinesterase regulation, higher dermal absorption per unit body weight, and frequent floor-level exposure to residues.
What is naled?
The IUPAC name is (1,2-dibromo-2,2-dichloroethyl) dimethyl phosphate.
Also known as: (1,2-dibromo-2,2-dichloroethyl) dimethyl phosphate, Dibrom, Bromchlophos, Bromex.
- IUPAC name
- (1,2-dibromo-2,2-dichloroethyl) dimethyl phosphate
- CAS number
- 300-76-5
- Molecular formula
- C4H7Br2Cl2O4P
- Molecular weight
- 380.78 g/mol
- SMILES
- COP(=O)(OC)OC(C(Cl)(Cl)Br)Br
- PubChem CID
- 4420
Risk for babies
High riskInfants are acutely vulnerable to Naled due to immature acetylcholinesterase regulation, higher dermal absorption per unit body weight, and frequent floor-level exposure to residues.
Neonates and infants up to 12 months have incomplete blood-brain barrier development, immature Phase I/II metabolic enzymes (particularly CYP3A4, UGT1A1), and higher gastrointestinal permeability. Equivalent doses produce higher internal concentrations and longer residence times.
Risk for pregnant and nursing people
Elevated riskPrenatal exposure to Naled is associated with neurodevelopmental effects. Organophosphate/carbamate insecticides inhibit acetylcholinesterase, which plays a role in fetal brain development.
Suspected reproductive toxicant (GHS H361) or suspected endocrine disruptor. Precautionary approach warranted. Animal studies or limited human data suggest developmental toxicity potential.
Regulatory consensus
8 regulatory and scientific bodies have classified Naled. The classifications differ — that's the data.
| Agency | Year | Classification | Notes |
|---|---|---|---|
| IARC | — | Group 2 | |
| EPA CTX / EPA OPP | — | Group E Evidence of Non-carcinogenicity for Humans | |
| EPA CTX / Skin-Eye | — | Eye Irritation: Eye Irrit. 2 (score: high) | |
| EPA CTX / Skin-Eye | — | Skin Irritation: Skin Irrit. 2 (score: high) | |
| EPA CTX / Skin-Eye | — | Skin Sensitization: Sh (score: high) | |
| EPA CTX / Skin-Eye | — | Eye Irritation: Category 2A (score: high) | |
| EPA CTX / Skin-Eye | — | Skin Irritation: Category 2 (score: high) | |
| EPA CTX / Skin-Eye | — | Skin Sensitization: Category 1 (score: high) |
Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.
Where kids encounter naled
- Industrial Facilities — Manufacturing plants, Chemical storage areas, Waste treatment sites
- Occupational Environments — Factories, Warehouses, Transportation vehicles
Safer alternatives
Lower-risk approaches that achieve a similar outcome to Naled:
-
Physical/mechanical pest control (IPM)
Trade-offs: More labor-intensive. May not be sufficient for severe infestations.Relative cost: 1.2-2×
Frequently asked questions
Is naled safe for kids?
Infants are acutely vulnerable to Naled due to immature acetylcholinesterase regulation, higher dermal absorption per unit body weight, and frequent floor-level exposure to residues.
What products contain naled?
Naled appears in: Manufacturing plants (Industrial facilities); Chemical storage areas (Industrial facilities); Factories (Occupational environments); Warehouses (Occupational environments).
What should I do if my child is exposed to naled?
Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.
Why do regulators disagree about naled?
Naled has been classified by 8 agencies including IARC, EPA CTX / EPA OPP, EPA CTX / Skin-Eye, EPA CTX / Skin-Eye, EPA CTX / Skin-Eye, with differing conclusions. Regulators apply different standards of evidence (animal data weighting, exposure-pattern assumptions, epidemiological power thresholds), which is why two scientific bodies can review the same data and reach different conclusions. See the regulatory consensus table on this page for the full picture.
See Naled in the baby app
Look up products containing naled, compare to alternatives, and explore the full data record.
Open in baby View raw API dataSources (1)
- US EPA: Naled Registration Review — Dichlorvos Metabolite, ULV Mosquito Control, Bystander Inhalation Risk, Pollinator and Aquatic Ecological Assessment (2016) (2016) — regulatory
Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →