Baby Safety / Compounds / Musk xylene

Is Musk xylene safe for babies and kids?

Context-dependent for kids

Infants are more vulnerable to Musk xylene than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

What is musk xylene?

Also known as: Musk xylol, Xylene musk, 2,4,6-Trinitro-1,3-dimethyl-5-tert-butylbenzene, 5-tert-Butyl-2,4,6-trinitro-m-xylene.

CAS number
81-15-2
Molecular formula
C12H15N3O6
Molecular weight
297.26 g/mol
SMILES
CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N+](=O)[O-])C)[N+](=O)[O-]
PubChem CID
62329

Risk for babies

Context-dependent

Infants are more vulnerable to Musk xylene than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

Neonates and infants up to 12 months have incomplete blood-brain barrier development, immature Phase I/II metabolic enzymes (particularly CYP3A4, UGT1A1), and higher gastrointestinal permeability. Equivalent doses produce higher internal concentrations and longer residence times.

What to do: Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

Risk for pregnant and nursing people

Context-dependent

Regulatory consensus

1 regulatory bodyhas classified Musk xylene.

AgencyYearClassificationNotes
EDC Assessment—Suspected endocrine disruptor

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter musk xylene

  • Personal Care — perfume, soap, cosmetics
  • Consumer Products — cleaning products, candles

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Musk xylene:

  • Lower-sensitization structural analog; Unscented formulation
    Trade-offs: Eliminates allergen risk entirely; consumer acceptance varies (some associate scent with cleanliness/efficacy); growing market segment; regulatory advantage in EU (no IFRA compliance needed).
    Relative cost: 1.2-2×

Frequently asked questions

Is musk xylene safe for kids?

Infants are more vulnerable to Musk xylene than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

What products contain musk xylene?

Musk xylene appears in: perfume (Personal care); soap (Personal care); cleaning products (Consumer products); candles (Consumer products).

What should I do if my child is exposed to musk xylene?

Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

See Musk xylene in the baby app

Look up products containing musk xylene, compare to alternatives, and explore the full data record.

Open in baby View raw API data

Sources (1)
  1. PubChem (2026) — database

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →