Baby Safety / Compounds / Hexachloroethane

Is Hexachloroethane safe for babies and kids?

Context-dependent for kids

(Babies-specific data is limited; this page draws from human pregnant context.) Pregnancy alters the metabolism and distribution of Hexachloroethane, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.

What is hexachloroethane?

The IUPAC name is 1,1,1,2,2,2-hexachloroethane.

Also known as: 1,1,1,2,2,2-hexachloroethane, Perchloroethane, Ethane, hexachloro-, Avlothane.

IUPAC name
1,1,1,2,2,2-hexachloroethane
CAS number
67-72-1
Molecular formula
C2Cl6
Molecular weight
236.7 g/mol
SMILES
C(C(Cl)(Cl)Cl)(Cl)(Cl)Cl
PubChem CID
6214

Risk for babies

Context-dependent

Pregnancy alters the metabolism and distribution of Hexachloroethane, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.

No specific reproductive toxicity data identified, but pregnancy-specific safety data is limited for most chemicals. Precautionary minimization of exposure is recommended.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Risk for pregnant and nursing people

Context-dependent

Pregnancy alters the metabolism and distribution of Hexachloroethane, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.

No specific reproductive toxicity data identified, but pregnancy-specific safety data is limited for most chemicals. Precautionary minimization of exposure is recommended.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Regulatory consensus

15 regulatory and scientific bodies have classified Hexachloroethane. The classifications differ — that's the data.

AgencyYearClassificationNotes
IARC1999Group 2B
US EPA1991probable human carcinogen
EPA CTX / NIOSHpotential occupational carcinogen
EPA CTX / IRISLikely to be carcinogenic to humans
EPA CTX / NTP RoCReasonably Anticipated to be a Human Carcinogen
EPA CTX / IARCGroup 2B - Possibly carcinogenic to humans
EPA CTX / EPA OPPGroup C Possible Human Carcinogen
EPA CTX / CalEPAKnown human carcinogen
EPA CTX / GenetoxGenotoxicity: negative (Ames: negative, 1 positive / 3 negative reports)
EPA CTX / GenetoxGenotoxicity: negative (Ames: negative, 1 positive / 3 negative reports)
EPA CTX / Skin-EyeSkin Irritation: SkinIrr2 (score: high)
EPA CTX / Skin-EyeEye Irritation: Serious eye damage/eye irritation - Category 2B (score: moderate)
EPA CTX / Skin-EyeEye Irritation: Category 2B (score: moderate)
EPA CTX / Skin-EyeSkin Irritation: Category 3 (score: moderate)
EPA CTX / Skin-EyeSkin Sensitization: Not classified (score: low)

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter hexachloroethane

  • Industrial FacilitiesManufacturing plants, Chemical storage areas, Waste treatment sites
  • Occupational EnvironmentsFactories, Warehouses, Transportation vehicles

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Hexachloroethane:

  • Process redesign to avoid hazardous intermediates
    Trade-offs: May require significant R&D investment. Not always feasible.
    Relative cost: 1.2-2×

Frequently asked questions

What products contain hexachloroethane?

Hexachloroethane appears in: Manufacturing plants (Industrial facilities); Chemical storage areas (Industrial facilities); Factories (Occupational environments); Warehouses (Occupational environments).

Why do regulators disagree about hexachloroethane?

Hexachloroethane has been classified by 15 agencies including IARC, US EPA, EPA CTX / NIOSH, EPA CTX / IRIS, EPA CTX / NTP RoC, with differing conclusions. Regulators apply different standards of evidence (animal data weighting, exposure-pattern assumptions, epidemiological power thresholds), which is why two scientific bodies can review the same data and reach different conclusions. See the regulatory consensus table on this page for the full picture.

See Hexachloroethane in the baby app

Look up products containing hexachloroethane, compare to alternatives, and explore the full data record.

Open in baby View raw API data

Sources (3)

  1. IARC Monographs Volume 73: Hexachloroethane — Group 2B; Hepatocellular Carcinomas in Female Mice; Inadequate Human Evidence; Metal Refining and Military Smoke Applications (1999) — iarc_monograph
  2. Stockholm Convention: Hexachloroethane Listed Under Review as POP — Persistence, Bioaccumulation, Toxicity Criteria; Military and Industrial Sources; Annex A Consideration (2009) — regulatory
  3. ATSDR Toxicological Profile: Hexachloroethane — Hepatotoxicity, Carcinogenicity in Mice, Military Smoke Munitions, Aluminum Refining Exposure, Aquatic Bioaccumulation (1996) — regulatory

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →