Baby Safety / Compounds / Flumioxazin

Is Flumioxazin safe for babies and kids?

Moderate risk for kids

Infants face elevated risk from Flumioxazin through dietary residues and environmental drift. Developing organ systems and immature detoxification capacity increase vulnerability.

What is flumioxazin?

Also known as: Valor, Broadstar, Flumyzin, S-53482.

CAS number: 103361-09-7
Molecular formula: C12H9FN2O4
Molecular weight: 354.33 g/mol
SMILES: C1C=CC2(C1)C(=O)N(c3cc4c(cc3F)OC(=O)C4=O)C2=O
PubChem CID: 92425

Risk for babies

Moderate risk

Infants face elevated risk from Flumioxazin through dietary residues and environmental drift. Developing organ systems and immature detoxification capacity increase vulnerability.

Neonates and infants up to 12 months have incomplete blood-brain barrier development, immature Phase I/II metabolic enzymes (particularly CYP3A4, UGT1A1), and higher gastrointestinal permeability. Equivalent doses produce higher internal concentrations and longer residence times.

What to do: Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

Risk for pregnant and nursing people

Elevated risk

Prenatal exposure to Flumioxazin is a concern due to potential endocrine disruption and developmental toxicity. Agricultural communities show higher gestational exposure through drinking water.

Suspected reproductive toxicant (GHS H361) or suspected endocrine disruptor. Precautionary approach warranted. Animal studies or limited human data suggest developmental toxicity potential.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Regulatory consensus

2 regulatory and scientific bodies have classified Flumioxazin. The classifications differ — that's the data.

Agency	Year	Classification	Notes
EPA	2001	Registered; developmental toxicant flag
EU	2003	Approved under Regulation (EC) 1107/2009; classified Repr. 2 H361d

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter flumioxazin

Agriculture
Water

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Flumioxazin:

Saflufenacil
Trade-offs: Newer chemistry, fewer use sites registered. Higher cost.

Relative cost: Higher

Frequently asked questions

Is flumioxazin safe for kids?

Infants face elevated risk from Flumioxazin through dietary residues and environmental drift. Developing organ systems and immature detoxification capacity increase vulnerability.

What should I do if my child is exposed to flumioxazin?

Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

See Flumioxazin in the baby app

Look up products containing flumioxazin, compare to alternatives, and explore the full data record.

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Sources (1)

EPA Registration — Flumioxazin — epa

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →