Baby Safety / Compounds / EDDS

Is EDDS safe for babies and kids?

Context-dependent for kids

(Babies-specific data is limited; this page draws from human pregnant context.) Pregnancy alters the metabolism and distribution of EDDS, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.

What is edds?

The IUPAC name is [S,S]-ethylenediamine-N,N'-disuccinic acid.

Also known as: [S,S]-ethylenediamine-N,N'-disuccinic acid, [S,S]-EDDS, ethylenediamine-N,N'-disuccinic acid, biodegradable EDTA alternative.

IUPAC name
[S,S]-ethylenediamine-N,N'-disuccinic acid
CAS number
20846-91-7
Molecular formula
C10H14N2Na2O8
Molecular weight
316.22 g/mol
SMILES
CCC1C2CC3C4C5(CC(C2C5C(=O)OCCl)N3C1O)C6=CC=CC=C6N4C
PubChem CID
92090

Risk for babies

Context-dependent

Pregnancy alters the metabolism and distribution of EDDS, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.

No specific reproductive toxicity data identified, but pregnancy-specific safety data is limited for most chemicals. Precautionary minimization of exposure is recommended.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Risk for pregnant and nursing people

Context-dependent

Pregnancy alters the metabolism and distribution of EDDS, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.

No specific reproductive toxicity data identified, but pregnancy-specific safety data is limited for most chemicals. Precautionary minimization of exposure is recommended.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Regulatory consensus

2 regulatory and scientific bodies have classified EDDS. The classifications differ — that's the data.

AgencyYearClassificationNotes
EU_CLPNot ClassifiedBelow hazard classification thresholds
OECDReadily biodegradable (OECD 301); >60% degradation at 28 days

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter edds

  • cosmetics
  • skincare products
  • phytoremediation
  • soil treatment

Safer alternatives

Lower-risk approaches that achieve a similar outcome to EDDS:

  • GLDA (tetrasodium glutamate diacetate) — readily biodegradable chelator
    Trade-offs: Extremely mild (pH 5.5-6.5); biodegradable; derived from amino acids and fatty acids; premium ingredient cost; excellent consumer perception; lower foam volume than sulfate surfactants.
    Relative cost: 1.2-2×
  • Citric acid — food-grade, naturally occurring
    Trade-offs: Alternative chelating agent; stability constants for target metal ions differ; biodegradability varies (EDTA poorly biodegradable, citrate fully biodegradable); downstream water treatment impact should be assessed.
    Relative cost: 2-5× conventional
  • MGDA (methylglycinediacetic acid) — high biodegradability
    Trade-offs: Alternative chelating agent; stability constants for target metal ions differ; biodegradability varies (EDTA poorly biodegradable, citrate fully biodegradable); downstream water treatment impact should be assessed.
    Relative cost: 1.2-2×

Frequently asked questions

What products contain edds?

EDDS appears in: cosmetics; skincare products; phytoremediation.

See EDDS in the baby app

Look up products containing edds, compare to alternatives, and explore the full data record.

Open in baby View raw API data

Sources (2)

  1. PubChem Compound CID 92090 — database
  2. ATSDR Toxicological Profile — CAS 20846-91-7 — reference

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →