Baby Safety / Compounds / Disperse Orange 3

Is Disperse Orange 3 safe for babies and kids?

Moderate risk for kids

Infants are more vulnerable to Disperse Orange 3 than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

What is disperse orange 3?

Also known as: 1-AMINO-2-METHYLANTHRAQUINONE, Disperse Orange 11, Disperse Orange, Celliton Orange R.

CAS number
82-28-0
Molecular formula
C15H11NO2
Molecular weight
237.25 g/mol
SMILES
CC1=C(C2=C(C=C1)C(=O)C3=CC=CC=C3C2=O)N
PubChem CID
6702

Risk for babies

Moderate risk

Infants are more vulnerable to Disperse Orange 3 than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

Neonates and infants up to 12 months have incomplete blood-brain barrier development, immature Phase I/II metabolic enzymes (particularly CYP3A4, UGT1A1), and higher gastrointestinal permeability. Equivalent doses produce higher internal concentrations and longer residence times.

What to do: Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

Risk for pregnant and nursing people

Context-dependent

Pregnancy alters the metabolism and distribution of Disperse Orange 3, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.

No specific reproductive toxicity data identified, but pregnancy-specific safety data is limited for most chemicals. Precautionary minimization of exposure is recommended.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Regulatory consensus

1 regulatory bodyhas classified Disperse Orange 3.

AgencyYearClassificationNotes
Unknown——

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter disperse orange 3

  • Consumer Products — personal care, industrial, food contact

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Disperse Orange 3:

  • Natural dyes; Undyed alternatives
    Trade-offs: Direct chemical substitution requires verification that the replacement does not introduce new hazards (regrettable substitution). Conduct full hazard assessment of proposed alternative before adoption.
    Relative cost: 2-5× conventional

Frequently asked questions

Is disperse orange 3 safe for kids?

Infants are more vulnerable to Disperse Orange 3 than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

What products contain disperse orange 3?

Disperse Orange 3 appears in: personal care (Consumer products); industrial (Consumer products).

What should I do if my child is exposed to disperse orange 3?

Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

See Disperse Orange 3 in the baby app

Look up products containing disperse orange 3, compare to alternatives, and explore the full data record.

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Sources (1)
  1. PubChem (2026) — database

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →