Baby Safety / Compounds / Diphacinone

Is Diphacinone safe for babies and kids?

Context-dependent for kids

(Babies-specific data is limited; this page draws from human pregnant context.) Pregnancy alters the metabolism and distribution of Diphacinone, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.

What is diphacinone?

The IUPAC name is 2-(2,2-diphenylacetyl)indene-1,3-dione.

Also known as: 2-(2,2-diphenylacetyl)indene-1,3-dione, DIPHENADIONE, Didandin, Diphenacin.

IUPAC name
2-(2,2-diphenylacetyl)indene-1,3-dione
CAS number
82-66-6
Molecular formula
C23H16O3
Molecular weight
340.4 g/mol
SMILES
C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)C3C(=O)C4=CC=CC=C4C3=O
PubChem CID
6719

Risk for babies

Context-dependent

Pregnancy alters the metabolism and distribution of Diphacinone, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.

No specific reproductive toxicity data identified, but pregnancy-specific safety data is limited for most chemicals. Precautionary minimization of exposure is recommended.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Risk for pregnant and nursing people

Context-dependent

Pregnancy alters the metabolism and distribution of Diphacinone, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.

No specific reproductive toxicity data identified, but pregnancy-specific safety data is limited for most chemicals. Precautionary minimization of exposure is recommended.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Regulatory consensus

1 regulatory bodyhas classified Diphacinone.

AgencyYearClassificationNotes
Unknown

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter diphacinone

  • Industrial FacilitiesManufacturing plants, Chemical storage areas, Waste treatment sites
  • Occupational EnvironmentsFactories, Warehouses, Transportation vehicles

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Diphacinone:

  • Physical/mechanical pest control (IPM)
    Trade-offs: More labor-intensive. May not be sufficient for severe infestations.
    Relative cost: 1.2-2×

Frequently asked questions

What products contain diphacinone?

Diphacinone appears in: Manufacturing plants (Industrial facilities); Chemical storage areas (Industrial facilities); Factories (Occupational environments); Warehouses (Occupational environments).

See Diphacinone in the baby app

Look up products containing diphacinone, compare to alternatives, and explore the full data record.

Open in baby View raw API data

Sources (2)

  1. US EPA: Rodenticide Cluster Registration Review — diphacinone, chlorophacinone, warfarin (FGARs); brodifacoum, bromadiolone, difethialone, difenacoum (SGARs); bromethalin; cholecalciferol; zinc phosphide; risk assessment; use restrictions; Hawaii native bird program (2020) (2020) — regulatory
  2. ASPCA Animal Poison Control Center: Rodenticide Toxicosis in Dogs and Cats — anticoagulant SGARs/FGARs; bromethalin; cholecalciferol; zinc phosphide; vitamin K1 dosing; decontamination windows; INR monitoring; prognosis by rodenticide class (2023) (2023) — veterinary

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →