Is Cyclohexanone safe for babies and kids?
High risk for kidsInfants are vulnerable to Cyclohexanone through inhalation of volatile residues in household products. Immature blood-brain barrier and higher respiratory rate per body weight amplify CNS exposure.
What is cyclohexanone?
Also known as: Ketohexamethylene, Pimelic ketone, Sextone, Nadone.
- CAS number
- 108-94-1
- Molecular formula
- C6H10O
- Molecular weight
- 98.14 g/mol
- SMILES
- C1CCC(=O)CC1
- PubChem CID
- 7967
Risk for babies
High riskInfants are vulnerable to Cyclohexanone through inhalation of volatile residues in household products. Immature blood-brain barrier and higher respiratory rate per body weight amplify CNS exposure.
Neonates and infants up to 12 months have incomplete blood-brain barrier development, immature Phase I/II metabolic enzymes (particularly CYP3A4, UGT1A1), and higher gastrointestinal permeability. Equivalent doses produce higher internal concentrations and longer residence times.
Risk for pregnant and nursing people
Context-dependentOccupational and household exposure to Cyclohexanone during pregnancy is associated with developmental toxicity. Solvents readily cross the placenta and can cause fetal growth restriction.
No specific reproductive toxicity data identified, but pregnancy-specific safety data is limited for most chemicals. Precautionary minimization of exposure is recommended.
Regulatory consensus
1 regulatory bodyhas classified Cyclohexanone.
| Agency | Year | Classification | Notes |
|---|---|---|---|
| Unknown | — | — |
Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.
Where kids encounter cyclohexanone
- Industrial Facilities — nylon production, paint/lacquer solvent, adhesives
Safer alternatives
Lower-risk approaches that achieve a similar outcome to Cyclohexanone:
-
Water-based systems
Trade-offs: Alternative solvent or process chemistry; solvency parameters (Hansen solubility, Kb value) must be matched to application; VOC content and flammability may differ; worker exposure assessment needed.Relative cost: 0.8-1.5×
-
Bio-based solvents
Trade-offs: Alternative solvent or process chemistry; solvency parameters (Hansen solubility, Kb value) must be matched to application; VOC content and flammability may differ; worker exposure assessment needed.Relative cost: 2-5× conventional
-
Methyl soyate
Trade-offs: Alternative solvent or process chemistry; solvency parameters (Hansen solubility, Kb value) must be matched to application; VOC content and flammability may differ; worker exposure assessment needed.Relative cost: 1.2-2×
Frequently asked questions
Is cyclohexanone safe for kids?
Infants are vulnerable to Cyclohexanone through inhalation of volatile residues in household products. Immature blood-brain barrier and higher respiratory rate per body weight amplify CNS exposure.
What products contain cyclohexanone?
Cyclohexanone appears in: nylon production (Industrial facilities); paint/lacquer solvent (Industrial facilities).
What should I do if my child is exposed to cyclohexanone?
Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.
See Cyclohexanone in the baby app
Look up products containing cyclohexanone, compare to alternatives, and explore the full data record.
Open in baby View raw API dataSources (1)
- PubChem Compound Database (2026) — database
Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →