Baby Safety / Compounds / Clomazone

Is Clomazone safe for babies and kids?

Elevated risk for kids

(Babies-specific data is limited; this page draws from human pregnant context.) Prenatal exposure to Clomazone is a concern due to potential endocrine disruption and developmental toxicity. Agricultural communities show higher gestational exposure through drinking water.

What is clomazone?

Also known as: Command, Dimethazone, FMC-57020, 2-(2-chlorobenzyl)-4,4-dimethyl-1,2-oxazolidin-3-one.

CAS number
81777-89-1
Molecular formula
C12H14ClNO2
Molecular weight
239.7 g/mol
SMILES
CC1(CON2C(=O)CCl2)c1ccccc1
PubChem CID
54778

Risk for babies

Elevated risk

Prenatal exposure to Clomazone is a concern due to potential endocrine disruption and developmental toxicity. Agricultural communities show higher gestational exposure through drinking water.

Suspected reproductive toxicant (GHS H361) or suspected endocrine disruptor. Precautionary approach warranted. Animal studies or limited human data suggest developmental toxicity potential.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Risk for pregnant and nursing people

Elevated risk

Prenatal exposure to Clomazone is a concern due to potential endocrine disruption and developmental toxicity. Agricultural communities show higher gestational exposure through drinking water.

Suspected reproductive toxicant (GHS H361) or suspected endocrine disruptor. Precautionary approach warranted. Animal studies or limited human data suggest developmental toxicity potential.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Regulatory consensus

2 regulatory and scientific bodies have classified Clomazone. The classifications differ — that's the data.

AgencyYearClassificationNotes
EPA2007Group E — Not carcinogenic
EU2007Approved under Regulation (EC) 1107/2009

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter clomazone

  • Agriculture
  • Water

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Clomazone:

  • Pendimethalin
    Trade-offs: Different mode of action (microtubule inhibition). Soil binding reduces leaching but may limit efficacy.
    Relative cost: Similar

Frequently asked questions

No FAQ entries generated.

See Clomazone in the baby app

Look up products containing clomazone, compare to alternatives, and explore the full data record.

Open in baby View raw API data

Sources (1)
  1. EPA Reregistration Eligibility Decision — Clomazone — epa

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →