Baby Safety / Compounds / Carbon disulfide (CS₂)

Is Carbon disulfide (CS₂) safe for babies and kids?

Elevated risk for kids

Infants are vulnerable to Carbon disulfide (CS₂) through inhalation of volatile residues in household products. Immature blood-brain barrier and higher respiratory rate per body weight amplify CNS exposure.

What is carbon disulfide (cs₂)?

The IUPAC name is methanedithione.

Also known as: methanedithione, CARBON DISULFIDE, Carbon disulphide, Carbon bisulfide.

IUPAC name
methanedithione
CAS number
75-15-0
Molecular formula
CS2
Molecular weight
76.15 g/mol
SMILES
C(=S)=S
PubChem CID
6348

Risk for babies

Elevated risk

Infants are vulnerable to Carbon disulfide (CS₂) through inhalation of volatile residues in household products. Immature blood-brain barrier and higher respiratory rate per body weight amplify CNS exposure.

Neonates and infants up to 12 months have incomplete blood-brain barrier development, immature Phase I/II metabolic enzymes (particularly CYP3A4, UGT1A1), and higher gastrointestinal permeability. Equivalent doses produce higher internal concentrations and longer residence times.

What to do: Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

Risk for pregnant and nursing people

Elevated risk

Occupational and household exposure to Carbon disulfide (CS₂) during pregnancy is associated with developmental toxicity. Solvents readily cross the placenta and can cause fetal growth restriction.

Suspected reproductive toxicant (GHS H361) or suspected endocrine disruptor. Precautionary approach warranted. Animal studies or limited human data suggest developmental toxicity potential.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Regulatory consensus

15 regulatory and scientific bodies have classified Carbon disulfide (CS₂). The classifications differ — that's the data.

AgencyYearClassificationNotes
IARCGroup 3
NIOSHOccupational exposure limit
OSHAOccupational exposure limit
MultipleReproductive toxicant
EPA CTX / GenetoxGenotoxicity: negative (Ames: negative, 2 positive / 7 negative reports)
EPA CTX / GenetoxGenotoxicity: negative (Ames: negative, 2 positive / 7 negative reports)
EPA CTX / Skin-EyeEye Irritation: Eye Irrit. 2 (score: high)
EPA CTX / Skin-EyeSkin Irritation: Skin Irrit. 2 (score: high)
EPA CTX / Skin-EyeEye Irritation: Category 2 (score: high)
EPA CTX / Skin-EyeSkin Irritation: Category 2 (score: high)
EPA CTX / Skin-EyeEye Irritation: Eye Irrit. 2 (score: high)
EPA CTX / Skin-EyeSkin Irritation: Skin Irrit. 2 (score: high)
EPA CTX / Skin-EyeEye Irritation: Category 6.4A (Category 2A) (score: high)
EPA CTX / Skin-EyeSkin Irritation: Category 6.3A (Category 2) (score: high)
EPA CTX / Skin-Eyeskin sensitisation: in vivo (LLNA): Not likely to be sensitizing (score: low)

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter carbon disulfide (cs₂)

  • Industrial FacilitiesManufacturing plants, Chemical storage areas, Waste treatment sites
  • Occupational EnvironmentsFactories, Warehouses, Transportation vehicles

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Carbon disulfide (CS₂):

  • Water-based formulations where feasible
    Trade-offs: Longer drying time. May not achieve same performance in all applications.
    Relative cost: 0.8-1.5×
  • Bio-based solvents (d-limonene, ethyl lactate)
    Trade-offs: Higher cost. Flammability concerns with some bio-solvents.
    Relative cost: 2-5× conventional

Frequently asked questions

Is carbon disulfide (cs₂) safe for kids?

Infants are vulnerable to Carbon disulfide (CS₂) through inhalation of volatile residues in household products. Immature blood-brain barrier and higher respiratory rate per body weight amplify CNS exposure.

What products contain carbon disulfide (cs₂)?

Carbon disulfide (CS₂) appears in: Manufacturing plants (Industrial facilities); Chemical storage areas (Industrial facilities); Factories (Occupational environments); Warehouses (Occupational environments).

What should I do if my child is exposed to carbon disulfide (cs₂)?

Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

Why do regulators disagree about carbon disulfide (cs₂)?

Carbon disulfide (CS₂) has been classified by 15 agencies including IARC, NIOSH, OSHA, Multiple, EPA CTX / Genetox, with differing conclusions. Regulators apply different standards of evidence (animal data weighting, exposure-pattern assumptions, epidemiological power thresholds), which is why two scientific bodies can review the same data and reach different conclusions. See the regulatory consensus table on this page for the full picture.

See Carbon disulfide (CS₂) in the baby app

Look up products containing carbon disulfide (cs₂), compare to alternatives, and explore the full data record.

Open in baby View raw API data

Sources (3)

  1. ATSDR Toxicological Profile: Carbon Disulfide — Neurotoxicity, Cardiovascular Effects, Reproductive Toxicity, Occupational Exposure, Viscose Rayon Industry Cohorts (1996) — regulatory
  2. NIOSH Criteria Document: Occupational Exposure to Carbon Disulfide — REL 1 ppm, Peripheral Neuropathy, Coronary Heart Disease, Reproductive Effects, Exposure Controls (1977) — regulatory
  3. Tolonen et al.: Vascular Effects of Carbon Disulfide Exposure — Viscose Rayon Worker Cohort, Accelerated Atherosclerosis, Coronary Heart Disease Excess Mortality, Finland (1975) — study

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →