Baby Safety / Compounds / Caprolactam

Is Caprolactam safe for babies and kids?

Context-dependent for kids

(Babies-specific data is limited; this page draws from human pregnant context.) Pregnancy alters the metabolism and distribution of Caprolactam, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.

What is caprolactam?

The IUPAC name is azepan-2-one.

Also known as: azepan-2-one, epsilon-Caprolactam, 2-Oxohexamethylenimine, 6-Caprolactam.

IUPAC name
azepan-2-one
CAS number
105-60-2
Molecular formula
C6H11NO
Molecular weight
113.16 g/mol
SMILES
O=C1CCCCCN1
PubChem CID
7768

Risk for babies

Context-dependent

Pregnancy alters the metabolism and distribution of Caprolactam, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.

No specific reproductive toxicity data identified, but pregnancy-specific safety data is limited for most chemicals. Precautionary minimization of exposure is recommended.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Risk for pregnant and nursing people

Context-dependent

Pregnancy alters the metabolism and distribution of Caprolactam, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.

No specific reproductive toxicity data identified, but pregnancy-specific safety data is limited for most chemicals. Precautionary minimization of exposure is recommended.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Regulatory consensus

3 regulatory and scientific bodies have classified Caprolactam. The classifications differ — that's the data.

AgencyYearClassificationNotes
EPA CTX / IARCGroup 3 - Not classifiable as to its carcinogenicity to humans
EPA CTX / GenetoxGenotoxicity: negative (Ames: negative, 0 positive / 9 negative reports)
EPA CTX / GenetoxGenotoxicity: negative (Ames: negative, 0 positive / 9 negative reports)

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter caprolactam

  • Industrial FacilitiesManufacturing plants, Waste treatment sites
  • Occupational EnvironmentsFactories, Warehouses

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Caprolactam:

  • Bio-based polymer alternatives where available
    Trade-offs: Performance limitations. End-of-life complexity.
    Relative cost: 2-5× conventional

Frequently asked questions

What products contain caprolactam?

Caprolactam appears in: Manufacturing plants (Industrial facilities); Waste treatment sites (Industrial facilities); Factories (Occupational environments); Warehouses (Occupational environments).

Why do regulators disagree about caprolactam?

Caprolactam has been classified by 3 agencies including EPA CTX / IARC, EPA CTX / Genetox, EPA CTX / Genetox, with differing conclusions. Regulators apply different standards of evidence (animal data weighting, exposure-pattern assumptions, epidemiological power thresholds), which is why two scientific bodies can review the same data and reach different conclusions. See the regulatory consensus table on this page for the full picture.

See Caprolactam in the baby app

Look up products containing caprolactam, compare to alternatives, and explore the full data record.

Open in baby View raw API data

Sources (3)

  1. PubChem Compound CID 7768 — database
  2. EPA CompTox Chemicals Dashboard — DTXSID4020240 — epa
  3. ATSDR Toxicological Profile — CAS 105-60-2 — reference

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →