Baby Safety / Compounds / Bromacil

Is Bromacil safe for babies and kids?

Moderate risk for kids

Infants face elevated risk from Bromacil through dietary residues and environmental drift. Developing organ systems and immature detoxification capacity increase vulnerability.

What is bromacil?

The IUPAC name is 5-bromo-3-butan-2-yl-6-methyl-1H-pyrimidine-2,4-dione.

Also known as: 5-bromo-3-butan-2-yl-6-methyl-1H-pyrimidine-2,4-dione, Uragan, Hyvar X, Borea.

IUPAC name
5-bromo-3-butan-2-yl-6-methyl-1H-pyrimidine-2,4-dione
CAS number
314-40-9
Molecular formula
C9H13BrN2O2
Molecular weight
261.12 g/mol
SMILES
CCC(C)N1C(=O)C(=C(NC1=O)C)Br
PubChem CID
9411

Risk for babies

Moderate risk

Infants face elevated risk from Bromacil through dietary residues and environmental drift. Developing organ systems and immature detoxification capacity increase vulnerability.

Neonates and infants up to 12 months have incomplete blood-brain barrier development, immature Phase I/II metabolic enzymes (particularly CYP3A4, UGT1A1), and higher gastrointestinal permeability. Equivalent doses produce higher internal concentrations and longer residence times.

What to do: Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

Risk for pregnant and nursing people

Elevated risk

Prenatal exposure to Bromacil is a concern due to potential endocrine disruption and developmental toxicity. Agricultural communities show higher gestational exposure through drinking water.

Suspected reproductive toxicant (GHS H361) or suspected endocrine disruptor. Precautionary approach warranted. Animal studies or limited human data suggest developmental toxicity potential.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Regulatory consensus

8 regulatory and scientific bodies have classified Bromacil. The classifications differ — that's the data.

AgencyYearClassificationNotes
EPA CTX / EPA OPP—Group C Possible Human Carcinogen
EPA CTX / Genetox—Genotoxicity: negative (Ames: negative, 0 positive / 8 negative reports)
EPA CTX / Genetox—Genotoxicity: negative (Ames: negative, 0 positive / 8 negative reports)
EPA CTX / Skin-Eye—Eye Irritation: Category 2B (score: moderate)
EPA CTX / Skin-Eye—Skin Irritation: Category 3 (score: moderate)
EPA CTX / Skin-Eye—Skin Sensitization: Not classified (score: low)
EPA CTX / Skin-Eye—Eye Irritation: Category 6.4A (Category 2A) (score: high)
EPA CTX / Skin-Eye—Skin Irritation: Category 6.3B (Category 3) (score: moderate)

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter bromacil

  • Industrial Facilities — Manufacturing plants, Chemical storage areas, Waste treatment sites
  • Occupational Environments — Factories, Warehouses, Transportation vehicles

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Bromacil:

  • Physical/mechanical pest control (IPM)
    Trade-offs: More labor-intensive. May not be sufficient for severe infestations.
    Relative cost: 1.2-2×

Frequently asked questions

Is bromacil safe for kids?

Infants face elevated risk from Bromacil through dietary residues and environmental drift. Developing organ systems and immature detoxification capacity increase vulnerability.

What products contain bromacil?

Bromacil appears in: Manufacturing plants (Industrial facilities); Chemical storage areas (Industrial facilities); Factories (Occupational environments); Warehouses (Occupational environments).

What should I do if my child is exposed to bromacil?

Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

Why do regulators disagree about bromacil?

Bromacil has been classified by 8 agencies including EPA CTX / EPA OPP, EPA CTX / Genetox, EPA CTX / Genetox, EPA CTX / Skin-Eye, EPA CTX / Skin-Eye, with differing conclusions. Regulators apply different standards of evidence (animal data weighting, exposure-pattern assumptions, epidemiological power thresholds), which is why two scientific bodies can review the same data and reach different conclusions. See the regulatory consensus table on this page for the full picture.

See Bromacil in the baby app

Look up products containing bromacil, compare to alternatives, and explore the full data record.

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Sources (1)
  1. US EPA: Bromacil Registration Eligibility Decision — Group C Carcinogen (Testicular Tumors), Groundwater Contamination, MCL, and Dietary Risk Assessment (2004) (2004) — regulatory

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →