Baby Safety / Compounds / Bisphenol P (BPP)

Is Bisphenol P (BPP) safe for babies and kids?

Moderate risk for kids

Infants are highly exposed to Bisphenol P (BPP) through mouthing of plastic toys, teethers, bottles, and food packaging leachates. Endocrine disruption risk is amplified during critical windows of reproductive and neurological development.

What is bisphenol p (bpp)?

The IUPAC name is 4-[2-[4-[2-(4-hydroxyphenyl)propan-2-yl]phenyl]propan-2-yl]phenol.

Also known as: 4-[2-[4-[2-(4-hydroxyphenyl)propan-2-yl]phenyl]propan-2-yl]phenol, Bisphenol P, 4,4'-(1,4-Phenylenediisopropylidene)bisphenol, 4-[1-[4-[1-(4-hydroxyphenyl)-1-methyl-ethyl]phenyl]-1-methyl-ethyl]phenol.

IUPAC name
4-[2-[4-[2-(4-hydroxyphenyl)propan-2-yl]phenyl]propan-2-yl]phenol
CAS number
2167-51-3
Molecular formula
C24H26O2
Molecular weight
346.5 g/mol
SMILES
CC(C)(C1=CC=C(C=C1)C(C)(C)C2=CC=C(C=C2)O)C3=CC=C(C=C3)O
PubChem CID
630355

Risk for babies

Moderate risk

Infants are highly exposed to Bisphenol P (BPP) through mouthing of plastic toys, teethers, bottles, and food packaging leachates. Endocrine disruption risk is amplified during critical windows of reproductive and neurological development.

Neonates and infants up to 12 months have incomplete blood-brain barrier development, immature Phase I/II metabolic enzymes (particularly CYP3A4, UGT1A1), and higher gastrointestinal permeability. Equivalent doses produce higher internal concentrations and longer residence times.

What to do: Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

Risk for pregnant and nursing people

Elevated risk

Prenatal exposure to Bisphenol P (BPP) is associated with endocrine disruption affecting fetal reproductive development. Phthalates and alternative plasticizers cross the placenta and are detectable in amniotic fluid.

Suspected reproductive toxicant (GHS H361) or suspected endocrine disruptor. Precautionary approach warranted. Animal studies or limited human data suggest developmental toxicity potential.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Regulatory consensus

1 regulatory bodyhas classified Bisphenol P (BPP).

AgencyYearClassificationNotes
ECHA (Bisphenol P not individually classified for carcinogenicity; structural bisphenol analog with a 1,4-phenylenediisopropylidene bridge; estrogenic activity documented in ER-binding assays; limited regulatory toxicology assessment as individual compound; no carcinogenicity classification by IARC, EFSA, NTP, or US EPA; detected in environmental matrices and human biomonitoring samples in some studies as BPA substitute)2022no carcinogenicity classification; bisphenol structural analog with documented estrogenic activity; limited regulatory assessment; not classified by IARC, EFSA, NTP, or US EPA for carcinogenicity

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter bisphenol p (bpp)

  • Consumer Products — Plastic bottles and containers, Food packaging, Plastic toys and household items
  • Drinking Water — Leaching from plastic pipes, Migration from bottled water containers
  • Indoor Environments — Off-gassing from plastic furniture, Degradation of plastic products

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Bisphenol P (BPP):

  • NSF-certified activated carbon filtration
    Trade-offs: Does not remove all contaminants. Requires filter replacement.
    Relative cost: 2-5× conventional

Frequently asked questions

Is bisphenol p (bpp) safe for kids?

Infants are highly exposed to Bisphenol P (BPP) through mouthing of plastic toys, teethers, bottles, and food packaging leachates. Endocrine disruption risk is amplified during critical windows of reproductive and neurological development.

What products contain bisphenol p (bpp)?

Bisphenol P (BPP) appears in: Plastic bottles and containers (Consumer products); Food packaging (Consumer products); Leaching from plastic pipes (Drinking water); Migration from bottled water containers (Drinking water); Off-gassing from plastic furniture (Indoor environments).

What should I do if my child is exposed to bisphenol p (bpp)?

Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

See Bisphenol P (BPP) in the baby app

Look up products containing bisphenol p (bpp), compare to alternatives, and explore the full data record.

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Sources (1)
  1. ECHA Bisphenol P CAS 2167-51-3 Structural Analog Estrogenic ER-Binding Activity; Limited Individual Regulatory Assessment; BPA Substitute Engineering Plastics Epoxy Resins; No IARC EFSA NTP EPA Carcinogenicity Classification; Environmental Detection Surface Water Sediment (2022) — regulatory

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →