Baby Safety / Compounds / Bisphenol F diglycidyl ether (BFDGE)

Is Bisphenol F diglycidyl ether (BFDGE) safe for babies and kids?

High risk for kids

Infants are highly exposed to Bisphenol F diglycidyl ether (BFDGE) through mouthing of plastic toys, teethers, bottles, and food packaging leachates. Endocrine disruption risk is amplified during critical windows of reproductive and neurological development.

What is bisphenol f diglycidyl ether (bfdge)?

The IUPAC name is 2-[[4-[[4-(oxiran-2-ylmethoxy)phenyl]methyl]phenoxy]methyl]oxirane.

Also known as: 2-[[4-[[4-(oxiran-2-ylmethoxy)phenyl]methyl]phenoxy]methyl]oxirane, Bisphenol F diglycidyl ether, BFDGE cpd, RefChem:917346.

IUPAC name: 2-[[4-[[4-(oxiran-2-ylmethoxy)phenyl]methyl]phenoxy]methyl]oxirane
CAS number: 2095-03-6
Molecular formula: C19H20O4
Molecular weight: 312.4 g/mol
SMILES: C(OC1=CC=C(CC2=CC=C(OCC3CO3)C=C2)C=C1)C1CO1
PubChem CID: 91511

Risk for babies

High risk

Neonates and infants up to 12 months have incomplete blood-brain barrier development, immature Phase I/II metabolic enzymes (particularly CYP3A4, UGT1A1), and higher gastrointestinal permeability. Equivalent doses produce higher internal concentrations and longer residence times.

What to do: Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

Risk for pregnant and nursing people

Elevated risk

GHS Warning classification. Endocrine disruptor — fetal exposure concern.

Regulatory consensus

1 regulatory bodyhas classified Bisphenol F diglycidyl ether (BFDGE).

Agency	Year	Classification	Notes
GHS	—	Skin hazard; inhalation hazard

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter bisphenol f diglycidyl ether (bfdge)

Consumer Products — Plastic bottles and containers, Food packaging
Indoor Environments — Off-gassing from plastic products

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Bisphenol F diglycidyl ether (BFDGE):

DINCH; DOTP; Citrate esters; Bio-based plasticizers
Trade-offs: Alternative plasticizer; compatibility with polymer matrix required; migration rate and toxicological profile of alternative should be assessed; mechanical properties (flexibility, tensile strength) may change.

Relative cost: 2-5× conventional

Frequently asked questions

Is bisphenol f diglycidyl ether (bfdge) safe for kids?

What products contain bisphenol f diglycidyl ether (bfdge)?

Bisphenol F diglycidyl ether (BFDGE) appears in: Plastic bottles and containers (Consumer products); Food packaging (Consumer products); Off-gassing from plastic products (Indoor environments).

What should I do if my child is exposed to bisphenol f diglycidyl ether (bfdge)?

Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

See Bisphenol F diglycidyl ether (BFDGE) in the baby app

Look up products containing bisphenol f diglycidyl ether (bfdge), compare to alternatives, and explore the full data record.

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Sources (3)

PubChem Compound CID 91511 — database
EPA CompTox Chemicals Dashboard — DTXSID4044872 — epa
ATSDR Toxicological Profile — CAS 2095-03-6 — reference

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →