Baby Safety / Compounds / beta-Damascone

Is beta-Damascone safe for babies and kids?

Moderate risk for kids

(Babies-specific data is limited; this page draws from human adult context.) beta-Damascone poses moderate risk to adults under typical exposure conditions.

What is beta-damascone?

The IUPAC name is 2,6,10-trimethylundeca-5,9-dien-2-one.

Also known as: 2,6,10-trimethylundeca-5,9-dien-2-one, Damasione, 4-(2,6,6-Trimethylcyclohex-1-enyl)but-2-en-4-one, (2E)-1-(2,6,6-trimethylcyclohex-1-en-1-yl)but-2-en-1-one.

IUPAC name
2,6,10-trimethylundeca-5,9-dien-2-one
CAS number
23726-91-2
Molecular formula
C13H20O
Molecular weight
192.3 g/mol
SMILES
CC=CC(=O)C1=C(CCCC1(C)C)C
PubChem CID
5374527

Risk for babies

Moderate risk

beta-Damascone poses moderate risk to adults under typical exposure conditions.

Regulatory consensus

2 regulatory and scientific bodies have classified beta-Damascone. The classifications differ — that's the data.

AgencyYearClassificationNotes
EU——EU Cosmetics Regulation (EC) No 1223/2009 - extended allergen declaration requirement
IFRA——IFRA Standards on Fragrance Materials

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter beta-damascone

  • Perfume
  • Personal Care
  • Fragrance Mixtures

Safer alternatives

Lower-risk approaches that achieve a similar outcome to beta-Damascone:

  • Fragrance-free product formulations
    Trade-offs: Eliminates allergen risk entirely; consumer acceptance varies (some associate scent with cleanliness/efficacy); growing market segment; regulatory advantage in EU (no IFRA compliance needed).
    Relative cost: Lower (ingredient elimination)
  • Essential oil-free synthetic fragrance blends with established safety profiles
    Trade-offs: Allows scent without specific natural allergens; synthetic molecules can be individually safety-tested; some synthetics have their own sensitization profiles; cost comparable to natural blends.
    Relative cost: Lower (ingredient elimination)
  • Encapsulated fragrance technologies (reduced dermal contact)
    Trade-offs: Reduces dermal contact by 60-90% via polymer shell release mechanism; higher formulation cost; may alter scent perception (delayed release); shell material itself requires safety assessment.
    Relative cost: 1.2-2×
  • Naturally-derived isolates at IFRA-compliant concentrations
    Trade-offs: Alternative fragrance ingredient; individual safety profile should be assessed per IFRA standards; sensitization potential varies by compound; patch testing recommended for sensitive individuals.
    Relative cost: 2-5× conventional

Frequently asked questions

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Sources (1)
  1. ATSDR Toxicological Profile — CAS 23726-91-2 — reference

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →