Baby Safety / Compounds / Azoxystrobin

Is Azoxystrobin safe for babies and kids?

Context-dependent for kids

(Babies-specific data is limited; this page draws from human pregnant context.) Pregnancy alters the metabolism and distribution of Azoxystrobin, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.

What is azoxystrobin?

The IUPAC name is methyl (E)-2-(2-(6-(2-cyanophenoxy)pyrimidin-4-yl)oxyacetyl)benzoate.

Also known as: methyl (E)-2-(2-(6-(2-cyanophenoxy)pyrimidin-4-yl)oxyacetyl)benzoate, Amistar, Bankit, Heritage.

IUPAC name
methyl (E)-2-(2-(6-(2-cyanophenoxy)pyrimidin-4-yl)oxyacetyl)benzoate
CAS number
131860-33-8
Molecular formula
C22H17N3O5
Molecular weight
403.39 g/mol
SMILES
COC=C(C1=CC=CC=C1OC2=NC=NC(=C2)OC3=CC=CC=C3C#N)C(=O)OC
PubChem CID
3034285

Risk for babies

Context-dependent

Pregnancy alters the metabolism and distribution of Azoxystrobin, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.

No specific reproductive toxicity data identified, but pregnancy-specific safety data is limited for most chemicals. Precautionary minimization of exposure is recommended.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Risk for pregnant and nursing people

Context-dependent

Pregnancy alters the metabolism and distribution of Azoxystrobin, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.

No specific reproductive toxicity data identified, but pregnancy-specific safety data is limited for most chemicals. Precautionary minimization of exposure is recommended.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Regulatory consensus

2 regulatory and scientific bodies have classified Azoxystrobin. The classifications differ — that's the data.

AgencyYearClassificationNotes
EPA
IARC

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter azoxystrobin

  • agricultural fungicide (cereals, fruits, vegetables)
  • turf fungicide
  • crop residues

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Azoxystrobin:

  • Trifloxystrobin (same QoI class, lower aquatic toxicity)
    Trade-offs: Same mode of action (FRAC Group 11) — cross-resistance. Lower aquatic toxicity profile.
    Relative cost: Similar
  • Copper hydroxide (inorganic fungicide)
    Trade-offs: Copper accumulation in soil. Lower efficacy for some diseases. Contact-only (no systemic activity).
    Relative cost: 0.5×

Frequently asked questions

What products contain azoxystrobin?

Azoxystrobin appears in: agricultural fungicide (cereals, fruits, vegetables); turf fungicide; crop residues.

See Azoxystrobin in the baby app

Look up products containing azoxystrobin, compare to alternatives, and explore the full data record.

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Sources (1)

  1. ATSDR Toxicological Profile — CAS 131860-33-8 — reference

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →