Baby Safety / Compounds / Atrazine

Is Atrazine safe for babies and kids?

Elevated risk for kids

Infants face elevated risk from Atrazine through dietary residues and environmental drift. Developing organ systems and immature detoxification capacity increase vulnerability.

What is atrazine?

The IUPAC name is 6-chloro-4-N-ethyl-2-N-propan-2-yl-1,3,5-triazine-2,4-diamine.

Also known as: 6-chloro-4-N-ethyl-2-N-propan-2-yl-1,3,5-triazine-2,4-diamine, Gesaprim, Aatrex, Atranex.

IUPAC name
6-chloro-4-N-ethyl-2-N-propan-2-yl-1,3,5-triazine-2,4-diamine
CAS number
1912-24-9
Molecular formula
C8H14ClN5
Molecular weight
215.68 g/mol
SMILES
CCNC1=NC(=NC(=N1)Cl)NC(C)C
PubChem CID
2256

Risk for babies

Elevated risk

Infants face elevated risk from Atrazine through dietary residues and environmental drift. Developing organ systems and immature detoxification capacity increase vulnerability.

Neonates and infants up to 12 months have incomplete blood-brain barrier development, immature Phase I/II metabolic enzymes (particularly CYP3A4, UGT1A1), and higher gastrointestinal permeability. Equivalent doses produce higher internal concentrations and longer residence times.

What to do: Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

Risk for pregnant and nursing people

Moderate risk

Animal fetal weight reduction; EPA MCL 3 ppb not protective for developmental exposure.

Regulatory consensus

12 regulatory and scientific bodies have classified Atrazine. The classifications differ — that's the data.

AgencyYearClassificationNotes
US EPAnot likely carcinogenprimary concern: endocrine disruption
EPA CTX / IARCGroup 3 - Not classifiable as to its carcinogenicity to humans
EPA CTX / EPA OPPNot Likely to Be Carcinogenic in Humans
EPA CTX / GenetoxGenotoxicity: negative (Ames: negative, 2 positive / 5 negative reports)
EPA CTX / GenetoxGenotoxicity: negative (Ames: negative, 2 positive / 5 negative reports)
EPA CTX / Skin-EyeSkin Sensitization: Skin Sens. 1 (score: high)
EPA CTX / Skin-EyeEye Irritation: Category 2B (score: moderate)
EPA CTX / Skin-EyeSkin Irritation: Not classified (score: low)
EPA CTX / Skin-EyeSkin Sensitization: Category 1 (score: high)
EPA CTX / Skin-Eyeskin irritation: in vivo: Moderate or Mild Irritation (score: moderate)
EPA CTX / Skin-Eyeeye irritation: in vivo: Studies Indicate No Significant Irritation (score: low)
EPA CTX / Skin-Eyeskin sensitisation: in vivo (non-LLNA): High Frequency of Sensitization (score: high)

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter atrazine

  • Industrial FacilitiesManufacturing plants, Chemical storage areas, Waste treatment sites
  • Occupational EnvironmentsFactories, Warehouses, Transportation vehicles

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Atrazine:

  • Physical/mechanical pest control (IPM)
    Trade-offs: More labor-intensive. May not be sufficient for severe infestations.
    Relative cost: 1.2-2×

Frequently asked questions

Is atrazine safe for kids?

Infants face elevated risk from Atrazine through dietary residues and environmental drift. Developing organ systems and immature detoxification capacity increase vulnerability.

What products contain atrazine?

Atrazine appears in: Manufacturing plants (Industrial facilities); Chemical storage areas (Industrial facilities); Factories (Occupational environments); Warehouses (Occupational environments).

What should I do if my child is exposed to atrazine?

Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

Why do regulators disagree about atrazine?

Atrazine has been classified by 12 agencies including US EPA, EPA CTX / IARC, EPA CTX / EPA OPP, EPA CTX / Genetox, EPA CTX / Genetox, with differing conclusions. Regulators apply different standards of evidence (animal data weighting, exposure-pattern assumptions, epidemiological power thresholds), which is why two scientific bodies can review the same data and reach different conclusions. See the regulatory consensus table on this page for the full picture.

See Atrazine in the baby app

Look up products containing atrazine, compare to alternatives, and explore the full data record.

Open in baby View raw API data

Sources (2)

  1. US EPA: Atrazine — Final Human Health Assessment (2016) — regulatory
  2. Hayes TB et al. Hermaphroditic, demasculinized frogs after exposure to the herbicide atrazine. PNAS. 2002;99(8):5476-5480. (2002) — journal

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →