Is Aniline safe for babies and kids?
Context-dependent for kids(Babies-specific data is limited; this page draws from human pregnant context.) Pregnancy alters the metabolism and distribution of Aniline, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.
What is aniline?
Also known as: Benzenamine, Phenylamine, Aminobenzene, Aminophen.
- IUPAC name
- aniline
- CAS number
- 62-53-3
- Molecular formula
- C6H7N
- Molecular weight
- 93.13 g/mol
- SMILES
- C1=CC=C(C=C1)N
- PubChem CID
- 6115
Risk for babies
Context-dependentPregnancy alters the metabolism and distribution of Aniline, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.
No specific reproductive toxicity data identified, but pregnancy-specific safety data is limited for most chemicals. Precautionary minimization of exposure is recommended.
Risk for pregnant and nursing people
Context-dependentPregnancy alters the metabolism and distribution of Aniline, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.
No specific reproductive toxicity data identified, but pregnancy-specific safety data is limited for most chemicals. Precautionary minimization of exposure is recommended.
Regulatory consensus
22 regulatory and scientific bodies have classified Aniline. The classifications differ — that's the data.
| Agency | Year | Classification | Notes |
|---|---|---|---|
| IARC | 1982 | Group 3 | |
| US EPA | 2000 | probable human carcinogen (Group B2) | |
| EPA CTX / IRIS | — | B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) | |
| EPA CTX / IARC | — | Group 2A - Probably carcinogenic to humans | |
| EPA CTX / Health Canada | — | Group III: CEPA (possibly carcinogenic to humans) | |
| EPA CTX / EPA OPP | — | Group B2 Probable Human Carcinogen | |
| EPA CTX / CalEPA | — | Known human carcinogen | |
| EPA CTX / Genetox | — | Genotoxicity: positive (Ames: negative, 20 positive / 14 negative reports) | |
| EPA CTX / Genetox | — | Genotoxicity: positive (Ames: negative, 20 positive / 14 negative reports) | |
| EPA CTX / Skin-Eye | — | Eye Irritation: Eye Dam. 1 (score: very high) | |
| EPA CTX / Skin-Eye | — | Skin Sensitization: Skin Sens. 1 (score: high) | |
| EPA CTX / Skin-Eye | — | Skin Sensitization: Sh (score: high) | |
| EPA CTX / Skin-Eye | — | Eye Irritation: Serious eye damage/eye irritation - Category 2A (score: high) | |
| EPA CTX / Skin-Eye | — | Skin Sensitization: Skin sensitization - Category 1 (score: high) | |
| EPA CTX / Skin-Eye | — | Eye Irritation: Category 2A (score: high) | |
| EPA CTX / Skin-Eye | — | Skin Irritation: Not classified (score: low) | |
| EPA CTX / Skin-Eye | — | Skin Sensitization: Category 1 (score: high) | |
| EPA CTX / Skin-Eye | — | Eye Irritation: Eye Dam. 1 (score: very high) | |
| EPA CTX / Skin-Eye | — | Skin Sensitization: Skin Sens. 1 (score: high) | |
| EPA CTX / Skin-Eye | — | Eye Irritation: Category 8.3A (Category 1) (score: very high) | |
| EPA CTX / Skin-Eye | — | Skin Irritation: Category 6.3A (Category 2) (score: high) | |
| EPA CTX / Skin-Eye | — | Skin Sensitization: Category 6.5B (Category 1) (score: moderate) |
Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.
Where kids encounter aniline
- Industrial Facilities — Manufacturing plants, Chemical storage areas, Waste treatment sites
- Occupational Environments — Factories, Warehouses, Transportation vehicles
Safer alternatives
Lower-risk approaches that achieve a similar outcome to Aniline:
-
Tocopherol (Vitamin E) based antioxidants
Trade-offs: Lower thermal stability than synthetic BHT/BHA for some polymer applications.Relative cost: 2-5× conventional
Frequently asked questions
What products contain aniline?
Aniline appears in: Manufacturing plants (Industrial facilities); Chemical storage areas (Industrial facilities); Factories (Occupational environments); Warehouses (Occupational environments).
Why do regulators disagree about aniline?
Aniline has been classified by 22 agencies including IARC, US EPA, EPA CTX / IRIS, EPA CTX / IARC, EPA CTX / Health Canada, with differing conclusions. Regulators apply different standards of evidence (animal data weighting, exposure-pattern assumptions, epidemiological power thresholds), which is why two scientific bodies can review the same data and reach different conclusions. See the regulatory consensus table on this page for the full picture.
See Aniline in the baby app
Look up products containing aniline, compare to alternatives, and explore the full data record.
Open in baby View raw API dataSources (2)
- IARC Monographs Volume 27: Some Aromatic Amines, Anthraquinones and Nitroso Compounds, and Inorganic Fluorides Used in Drinking-Water and Dental Preparations — Aniline Group 3; Methemoglobin-Forming Compound; Splenic Hemangiosarcomas in Rodents; MDI/Dye/Rubber Chemical Intermediate (1982) — iarc_monograph
- US EPA Aniline: Group B2 Probable Carcinogen; Skin Absorption Major Exposure Route; OSHA PEL 5 ppm Skin; Methemoglobinemia; Phenylhydroxylamine Metabolite; Hemoglobin Adduct Monitoring; Moderate Aquatic Toxicity; Aerobic Biodegradable (2000) — regulatory
Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →