Baby Safety / Compounds / alpha-Amylcinnamaldehyde

Is alpha-Amylcinnamaldehyde safe for babies and kids?

Elevated risk for kids

Infants are more vulnerable to alpha-Amylcinnamaldehyde than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

What is alpha-amylcinnamaldehyde?

The IUPAC name is 2-benzylideneheptanal.

Also known as: 2-benzylideneheptanal, Amylcinnamaldehyde, Heptanal, 2-(phenylmethylene)-, FEMA No. 2061.

IUPAC name
2-benzylideneheptanal
CAS number
122-40-7
Molecular formula
C14H18O
Molecular weight
202.29 g/mol
SMILES
CCCCCC(=CC1=CC=CC=C1)C=O
PubChem CID
31209

Risk for babies

Elevated risk

Infants are more vulnerable to alpha-Amylcinnamaldehyde than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

Neonates and infants up to 12 months have incomplete blood-brain barrier development, immature Phase I/II metabolic enzymes (particularly CYP3A4, UGT1A1), and higher gastrointestinal permeability. Equivalent doses produce higher internal concentrations and longer residence times.

What to do: Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

Risk for pregnant and nursing people

Context-dependent

Prenatal exposure to alpha-Amylcinnamaldehyde through personal care products may affect fetal development. Some fragrance chemicals are sensitizers or endocrine-active compounds with transplacental transfer.

No specific reproductive toxicity data identified, but pregnancy-specific safety data is limited for most chemicals. Precautionary minimization of exposure is recommended.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Regulatory consensus

2 regulatory and scientific bodies have classified alpha-Amylcinnamaldehyde. The classifications differ — that's the data.

AgencyYearClassificationNotes
IFRA2020restrictionIFRA restriction — sensitization limits by category
EU_COSMETICS2009allergen_disclosureEU Annex III original 26 allergens

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter alpha-amylcinnamaldehyde

  • Personal Care — perfume, soap, shampoo, cosmetics
  • Consumer Products — cleaning products, candles, air fresheners
  • Fragrance — perfume, cologne, scented personal care products, household fragrance products, candles
    Identified in Fragrance Ingredient Safety Priority Research database (2,325 ingredients)

Safer alternatives

Lower-risk approaches that achieve a similar outcome to alpha-Amylcinnamaldehyde:

  • Cyclamen aldehyde
    Trade-offs: Alternative fragrance ingredient; individual safety profile should be assessed per IFRA standards; sensitization potential varies by compound; patch testing recommended for sensitive individuals.
    Relative cost: 1.2-2×
  • Bourgeonal
    Trade-offs: Alternative fragrance ingredient; individual safety profile should be assessed per IFRA standards; sensitization potential varies by compound; patch testing recommended for sensitive individuals.
    Relative cost: 1.2-2×

Frequently asked questions

Is alpha-amylcinnamaldehyde safe for kids?

Infants are more vulnerable to alpha-Amylcinnamaldehyde than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

What products contain alpha-amylcinnamaldehyde?

alpha-Amylcinnamaldehyde appears in: perfume (Personal care); soap (Personal care); cleaning products (Consumer products); candles (Consumer products); perfume (Fragrance).

What should I do if my child is exposed to alpha-amylcinnamaldehyde?

Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

See alpha-Amylcinnamaldehyde in the baby app

Look up products containing alpha-amylcinnamaldehyde, compare to alternatives, and explore the full data record.

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Sources (1)
  1. PubChem Compound Database (2026) — database

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →