Baby Safety / Compounds / 25I-NBOMe

Is 25I-NBOMe safe for babies and kids?

Severe risk for kids

Infants are more vulnerable to 25I-NBOMe than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

What is 25i-nbome?

The IUPAC name is 2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine.

Also known as: Cimbi-5, N-bomb compound, 11C-CIMBI-5, 2C-I-NMBOMe.

IUPAC name
2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine
CAS number
919797-19-6
Molecular formula
C18H22INO3
Molecular weight
427.3 g/mol
SMILES
COc1cc(CCNCc2ccccc2OC)c(OC)cc1I
PubChem CID
10251906

Risk for babies

Severe risk

Infants are more vulnerable to 25I-NBOMe than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

Neonates and infants up to 12 months have incomplete blood-brain barrier development, immature Phase I/II metabolic enzymes (particularly CYP3A4, UGT1A1), and higher gastrointestinal permeability. Equivalent doses produce higher internal concentrations and longer residence times.

What to do: Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

Risk for pregnant and nursing people

Context-dependent

Pregnancy alters the metabolism and distribution of 25I-NBOMe, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.

No specific reproductive toxicity data identified, but pregnancy-specific safety data is limited for most chemicals. Precautionary minimization of exposure is recommended.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Regulatory consensus

1 regulatory bodyhas classified 25I-NBOMe.

AgencyYearClassificationNotes
DEA2013Schedule I controlled substance

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter 25i-nbome

  • Illicit Drug
  • Research Chemical

Safer alternatives

Lower-risk approaches that achieve a similar outcome to 25I-NBOMe:

  • No safe consumer alternative exists
    Trade-offs: N/A — extremely potent 5-HT2A agonist. Active at sub-milligram doses. Frequently sold as LSD on blotter. Multiple fatalities.
    Relative cost: N/A

Frequently asked questions

Is 25i-nbome safe for kids?

Infants are more vulnerable to 25I-NBOMe than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

What should I do if my child is exposed to 25i-nbome?

Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

See 25I-NBOMe in the baby app

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Sources (1)
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Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →