Is 2-Octyl-2H-isothiazol-3-one (OIT) safe for babies and kids?
Very high risk for kids(Babies-specific data is limited; this page draws from human pregnant context.) Pregnancy alters the metabolism and distribution of 2-Octyl-2H-isothiazol-3-one (OIT), potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.
What is 2-octyl-2h-isothiazol-3-one (oit)?
The IUPAC name is 1,2-benzothiazol-3-one.
Also known as: 1,2-benzothiazol-3-one, 1,2-Benzisothiazol-3(2H)-one, 1,2-Benzisothiazolin-3-one, benzisothiazolone.
- IUPAC name
- 1,2-benzothiazol-3-one
- CAS number
- 26530-20-1
- Molecular formula
- C7H5NOS
- Molecular weight
- 151.19 g/mol
- SMILES
- O=C1NSC2=C1C=CC=C2
- PubChem CID
- 17520
Risk for babies
Very high riskPregnancy alters the metabolism and distribution of 2-Octyl-2H-isothiazol-3-one (OIT), potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.
Suspected reproductive toxicant (GHS H361) or suspected endocrine disruptor. Precautionary approach warranted. Animal studies or limited human data suggest developmental toxicity potential.
Risk for pregnant and nursing people
Very high riskPregnancy alters the metabolism and distribution of 2-Octyl-2H-isothiazol-3-one (OIT), potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.
Suspected reproductive toxicant (GHS H361) or suspected endocrine disruptor. Precautionary approach warranted. Animal studies or limited human data suggest developmental toxicity potential.
Regulatory consensus
2 regulatory and scientific bodies have classified 2-Octyl-2H-isothiazol-3-one (OIT). The classifications differ — that's the data.
| Agency | Year | Classification | Notes |
|---|---|---|---|
| EPA CTX / Genetox | — | Genotoxicity: negative (Ames: negative, 1 positive / 5 negative reports) | |
| EPA CTX / Genetox | — | Genotoxicity: negative (Ames: negative, 1 positive / 5 negative reports) |
Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.
Where kids encounter 2-octyl-2h-isothiazol-3-one (oit)
- Industrial Facilities — Manufacturing plants, Waste treatment sites
- Occupational Environments — Factories, Warehouses
Safer alternatives
Lower-risk approaches that achieve a similar outcome to 2-Octyl-2H-isothiazol-3-one (OIT):
-
Physical/mechanical pest control (IPM)
Trade-offs: More labor-intensive. May not be sufficient for severe infestations.Relative cost: 1.2-2×
Frequently asked questions
What products contain 2-octyl-2h-isothiazol-3-one (oit)?
2-Octyl-2H-isothiazol-3-one (OIT) appears in: Manufacturing plants (Industrial facilities); Waste treatment sites (Industrial facilities); Factories (Occupational environments); Warehouses (Occupational environments).
See 2-Octyl-2H-isothiazol-3-one (OIT) in the baby app
Look up products containing 2-octyl-2h-isothiazol-3-one (oit), compare to alternatives, and explore the full data record.
Open in baby View raw API dataSources (3)
- PubChem Compound CID 17520 — database
- EPA CompTox Chemicals Dashboard — DTXSID5032523 — epa
- ATSDR Toxicological Profile — CAS 2634-33-5 — reference
Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →