Is 2-Methylquinoline (quinaldine) safe for babies and kids?
Elevated risk for kidsInfants are more vulnerable to 2-Methylquinoline (quinaldine) than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.
What is 2-methylquinoline (quinaldine)?
The IUPAC name is 2-methylquinoline.
Also known as: 2-methylquinoline, Quinaldine, Khinaldin, Chinaldine.
- IUPAC name
- 2-methylquinoline
- CAS number
- 91-63-4
- Molecular formula
- C10H9N
- Molecular weight
- 143.18 g/mol
- SMILES
- CC1=NC2=CC=CC=C2C=C1
- PubChem CID
- 7060
Risk for babies
Elevated riskInfants are more vulnerable to 2-Methylquinoline (quinaldine) than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.
Neonates and infants up to 12 months have incomplete blood-brain barrier development, immature Phase I/II metabolic enzymes (particularly CYP3A4, UGT1A1), and higher gastrointestinal permeability. Equivalent doses produce higher internal concentrations and longer residence times.
Risk for pregnant and nursing people
Context-dependentPrenatal exposure to 2-Methylquinoline (quinaldine) through personal care products may affect fetal development. Some fragrance chemicals are sensitizers or endocrine-active compounds with transplacental transfer.
No specific reproductive toxicity data identified, but pregnancy-specific safety data is limited for most chemicals. Precautionary minimization of exposure is recommended.
Regulatory consensus
1 regulatory bodyhas classified 2-Methylquinoline (quinaldine).
| Agency | Year | Classification | Notes |
|---|---|---|---|
| PROP_65 | 2012 | carcinogen | California Prop 65 — listed as carcinogen |
Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.
Where kids encounter 2-methylquinoline (quinaldine)
- Personal Care — fragrance formulations
-
Fragrance
— perfume, cologne, scented personal care products, household fragrance products, candles
Identified in Fragrance Ingredient Safety Priority Research database (2,325 ingredients)
Safer alternatives
Lower-risk approaches that achieve a similar outcome to 2-Methylquinoline (quinaldine):
-
Exposure reduction / process control
Trade-offs: Requires R&D investment to redesign synthesis routes; may reduce yield or throughput initially; long-term benefits include reduced waste treatment costs, regulatory compliance, and worker safety; 12 Principles of Green Chemistry framework available.Relative cost: 1.2-2×
Frequently asked questions
Is 2-methylquinoline (quinaldine) safe for kids?
Infants are more vulnerable to 2-Methylquinoline (quinaldine) than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.
What products contain 2-methylquinoline (quinaldine)?
2-Methylquinoline (quinaldine) appears in: fragrance formulations (Personal care); perfume (Fragrance); cologne (Fragrance).
What should I do if my child is exposed to 2-methylquinoline (quinaldine)?
Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.
See 2-Methylquinoline (quinaldine) in the baby app
Look up products containing 2-methylquinoline (quinaldine), compare to alternatives, and explore the full data record.
Open in baby View raw API dataSources (1)
- PubChem Compound Database (2026) — database
Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →