Baby Safety / Compounds / 2-Ethyl-3,5-dimethylpyrazine

Is 2-Ethyl-3,5-dimethylpyrazine safe for babies and kids?

Context-dependent for kids

(Babies-specific data is limited; this page draws from human pregnant context.) Pregnancy alters the metabolism and distribution of 2-Ethyl-3,5-dimethylpyrazine, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.

What is 2-ethyl-3,5-dimethylpyrazine?

Also known as: 3-Ethyl-2,5-dimethylpyrazine, 2-Ethyl-3,6-dimethylpyrazine, Pyrazine, 3-ethyl-2,5-dimethyl-, G2FB13VLOG.

IUPAC name
2-ethyl-3,5-dimethylpyrazine
CAS number
13360-65-1
Molecular formula
C8H12N2
Molecular weight
136.20 g/mol
SMILES
CCC1=NC(=CN=C1C)C
PubChem CID
25916

Risk for babies

Context-dependent

Pregnancy alters the metabolism and distribution of 2-Ethyl-3,5-dimethylpyrazine, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.

No specific reproductive toxicity data identified, but pregnancy-specific safety data is limited for most chemicals. Precautionary minimization of exposure is recommended.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Risk for pregnant and nursing people

Context-dependent

Pregnancy alters the metabolism and distribution of 2-Ethyl-3,5-dimethylpyrazine, potentially increasing fetal exposure. The developing embryo/fetus is vulnerable during organogenesis (weeks 3-8) and neurological development. Placental transfer should be assumed.

No specific reproductive toxicity data identified, but pregnancy-specific safety data is limited for most chemicals. Precautionary minimization of exposure is recommended.

What to do: Minimize exposure during pregnancy and lactation. Consult healthcare provider regarding specific risks. Consider alternative products with lower hazard profiles.

Regulatory consensus

2 regulatory and scientific bodies have classified 2-Ethyl-3,5-dimethylpyrazine. The classifications differ — that's the data.

AgencyYearClassificationNotes
FDA——
EFSA——

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter 2-ethyl-3,5-dimethylpyrazine

  • hazelnut flavoring
  • roasted flavoring
  • chocolate flavoring

Safer alternatives

Lower-risk approaches that achieve a similar outcome to 2-Ethyl-3,5-dimethylpyrazine:

  • Natural pyrazine complex from roasted barley malt
    Trade-offs: Contains mixture of pyrazines — less precise. Additional malt flavors.
    Relative cost: 1.5×

Frequently asked questions

What products contain 2-ethyl-3,5-dimethylpyrazine?

2-Ethyl-3,5-dimethylpyrazine appears in: hazelnut flavoring; roasted flavoring; chocolate flavoring.

See 2-Ethyl-3,5-dimethylpyrazine in the baby app

Look up products containing 2-ethyl-3,5-dimethylpyrazine, compare to alternatives, and explore the full data record.

Open in baby View raw API data

Sources (1)
  1. ATSDR Toxicological Profile — CAS 13360-65-1 — reference

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →