Baby Safety / Compounds / 1,3-Dichloropropene

Is 1,3-Dichloropropene safe for babies and kids?

Very high risk for kids

Infants are more vulnerable to 1,3-Dichloropropene than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

What is 1,3-dichloropropene?

Also known as: 1-Propene, 1,3-dichloro-, 1,3-Dichloro-1-propene, Dorlone, Telone.

CAS number
542-75-6
Molecular formula
C3H4Cl2
Molecular weight
110.97 g/mol
SMILES
C(C=CCl)Cl
PubChem CID
24883

Risk for babies

Very high risk

Infants are more vulnerable to 1,3-Dichloropropene than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

Neonates and infants up to 12 months have incomplete blood-brain barrier development, immature Phase I/II metabolic enzymes (particularly CYP3A4, UGT1A1), and higher gastrointestinal permeability. Equivalent doses produce higher internal concentrations and longer residence times.

What to do: Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

Risk for pregnant and nursing people

Context-dependent

Regulatory consensus

1 regulatory bodyhas classified 1,3-Dichloropropene.

AgencyYearClassificationNotes
EDC AssessmentSuspected endocrine disruptor

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where kids encounter 1,3-dichloropropene

  • Industrial Facilitiessoil fumigation, preplant crop treatment

Safer alternatives

Lower-risk approaches that achieve a similar outcome to 1,3-Dichloropropene:

  • Solarization
    Trade-offs: Alternative approach; specific tradeoffs depend on application context, scale, and regulatory requirements. Full hazard assessment of alternative recommended before adoption to avoid regrettable substitution.
    Relative cost: 1.2-2×
  • Biofumigation (mustard meal)
    Trade-offs: Alternative approach; specific tradeoffs depend on application context, scale, and regulatory requirements. Full hazard assessment of alternative recommended before adoption to avoid regrettable substitution.
    Relative cost: 1.2-2×
  • Steam sterilization
    Trade-offs: Alternative approach; specific tradeoffs depend on application context, scale, and regulatory requirements. Full hazard assessment of alternative recommended before adoption to avoid regrettable substitution.
    Relative cost: 1.2-2×

Frequently asked questions

Is 1,3-dichloropropene safe for kids?

Infants are more vulnerable to 1,3-Dichloropropene than children or adults due to immature hepatic/renal clearance, higher intake-to-body-weight ratio, rapid organ development, and increased gastrointestinal absorption.

What products contain 1,3-dichloropropene?

1,3-Dichloropropene appears in: soil fumigation (Industrial facilities); preplant crop treatment (Industrial facilities).

What should I do if my child is exposed to 1,3-dichloropropene?

Minimize infant exposure through source control. For breastfeeding mothers: reduce maternal exposure. For formula-fed infants: use certified low-migration bottles and verified water sources. Consult pediatrician regarding any concerns.

See 1,3-Dichloropropene in the baby app

Look up products containing 1,3-dichloropropene, compare to alternatives, and explore the full data record.

Open in baby View raw API data

Sources (1)

  1. PubChem Compound Database (2026) — database

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →